Alpha-IU CattleBox Concentrate 30 doses

This therapy applies to the following species: Dairy and Beef Cattle

1. The information provided typically including the following:

2. DESCRIPTION

3. INDICATIONS

Add 500ml of sterile water to 250 ml of concentrate AlphaIU. 750 ml of mixed product =30 doses.

ALPHA IU is indicated for the therapy of subacute and endometritis in cows caused by Actinomyces (Corynebacterium) pyogenes, Fusobacterium necrophorum and pigment-forming Bacteroides strains.

To accurately diagnose subacute or chronic endometritis, a vaginoscopic examination should be done to confirm the presence of a discharge from the cervix.

4. DOSAGE AND ADMINISTRATION

Thoroughly clean the vulvar area, maintain aseptic conditions and contaminate the catheter in preparation for the infusion.

Introduce a single dose of 25ml into the lumen of the uterus using a disposable catheter. Catheter is for one use only. Fix the syringe to the catheter, then take the cervix into a gloved hand introduced into the retum; introduce the catheter through the cervix into the lumen of the uterus by gently oscillating movement of the cervix. Inject the contents of the syringe.

One therapy session is usually sufficient for a complete cure. If the quantity and quality of the cervical discharge is not improved at examination 14 days after therapy, the cow should receive a second therapy. Other contaminating organisms not sensitive to cephapirin may be the cause of the infection and accurate laboratory diagnosis may be necessary. In inseminated animals, ALPHA IU can be used one day following insemination.

Note:

User of the product should be based on susceptibility testing of the bacteria from the animal. If this is not possible should be based on local (regional, farm level) epidemiological information about susceptibility of the target bacteria.

(Keep out of reach of children).

5. PHARMACOLOGY

ALPHA UI is a first generation non chemical therapy for a broad spectrum formulated with bactericidal action against sensitive gram-positive and gram-negative anaerobic bacteria. It is resistant to the action of penicillinase and is active in an anaerobic environment as encountered in an infected uterus. After a single treatment with ALPHA IU endometrial tissue above the MIC of sensitive bacteria are maintained for at least 36 to 48 hours

The suspension is easily infused and is well tolerated with good diffusion into the endometrium. 

6. STORAGE

Store in a dry place between 15° and 25°

7. SUPPLY

250 ml bottle of ALPHA IU concentrate and 30 catheters (single use only). For 30 doses.